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The next generation of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of lung cancer
CAS Number: 1426152-53-5
which covalently modifies Cys481
Negative and positive allosteric modulators of the P2X(7) receptor
AZD-2281 (Olaparib) is a single digit nanomolar inhibitor of both PARP-1 and PARP-2 that shows standalone activity against BRCA1-deficient breast cancer cell lines
Netupitant metabolite N-desmethyl Netupitant ciclib) The next generation of epidermalN desmethyl Netupitant is a metabolite of an antiemitic drug called Netupitant. Product information CAS Number: 290296 72 9 Molecular Weight: 564. 57 Formula: C29H30F6N4O Synonym: N desmethyl Netupitant Chemical Name: 2 [3,5 bis(trifluoromethyl)phenyl] N,2 dimethyl N [4 (2 methylphenyl) 6 (piperazin 1 yl)pyridin 3 yl]propanamide Smiles: CC(C)(C(=O)N(C)C1=CN=C(C=C1C1=CC=CC=C1C)N1CCNCC1)C1C=C(C=C(C=1)C(F)(F)F)C(F)(F)F InChiKey: SRVSDBHUBFLSFE UHFFFAOYSA